Autoinflammation

&

Hyperinflammation

IL-18

Autoinflammation

Systemic or organ-specific inflammation not attributable to infection, malignancy, or antigen-specific autoimmunity.

 

vs

 

Hyperinflammation

is a state of damaging immune activation that is excessive or disproportionate to what would be expected for a patient’s clinical context.

 

Categories of Immune Dysregulation

Focused on patients, their disease mechanisms, and training the next generation of translational investigators

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